Dear all,

See below for a post-doc opportunity with Erick Matsen’s group.

Cheers

Jeremy

From: Erick Matsen ematsen@gmail.com Sent: Wednesday, 20 January 2021 8:35 AM To: Erick Matsen ematsen@gmail.com Subject: Postdoc opening! Bayesian evolutionary algorithms for the analysis of B cell receptor (i.e. antibody) sequence lineages

Dear Colleague--

I hope you are doing as well as could be hoped for given the circumstances, and I apologize for the mass email.

We have a postdoc opening! Here's the headline:

The goal of our project is to develop, implement, and apply Bayesian evolutionary algorithms for the analysis of B cell receptor sequence lineages. These lineages are important for understanding the events leading to the development of high-affinity antibodies.

We are motivated to:

* use a Bayesian approach to appropriately account for uncertainty in phylogenetic inferences (which is considerable in this case) * fit and use complex models of somatic hypermutation and selection that violate the commonly-applied IID assumption in phylogenetics * develop efficient, elegant, and robust implementations of the newly developed methodology and make them available in open-source software for the community. Here's the full description: https://matsen.fredhutch.org/general/2021/01/15/bcell-postdoc.htmlhttps://protect-au.mimecast.com/s/GOAmCjZryVCq99xoCWC4yf?domain=matsen.fredhutch.org

If you know any trainees who might be interested in working in this area, please let me know!

I also note that we may have a slot to work on variational Bayes approaches to phylogenetics, but that will be dependent on funding. Nevertheless, if you know someone who would be interested in helping build fundamentally new approaches to Bayesian phylogenetics, I'd be happy to get to know them!

Members of underrepresented groups are especially encouraged to apply.

Thank you,

Erick

-- Frederick "Erick" Matsen (he/him) Professor, Fred Hutchinson Cancer Research Center http://matsen.fredhutch.org/https://protect-au.mimecast.com/s/Z-9UCk8vzVfQNNJ2tVM9zk?domain=matsen.fredhutch.org/

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